Carlyle Blackwell as Sherlock Holmes

George Seroff as Dr. Watson

Alexander Murski as Lord Charles Baskerville

Livio Pavanelli as Sir Henry Baskerville

Betty Bird as Beryl

Fritz Rasp as Stapleton

Valy Arnheim as Barrymore

Alma Taylor as Mrs. Barrymore

Carla Bartheel as Laura Lyons

Jaro Fürth as Dr. Mortimer

Robert Garrison as Falkland