Margaret Qualley as Sister Cathleen

Melissa Leo as Reverend Mother

Julianne Nicholson as Nora Harris

Dianna Agron as Sister Mary Grace

Lisa Stewart as Sister Genevieve

Morgan Saylor as Sister Evelyn

Liana Liberato as Sister Emily

Rebecca Dayan as Sister Emanuel

Eline Powell as Sister Candace

Chelsea Lopez as Sister Charlotte

Maddie Hasson as Sister Sissy

Denis O'Hare as Archbishop

Chris Zylka as Chuck Harris

Alyssa Brindley as Sister Kate

Hannah Renèe Jackson as Sister Anne

Marco St. John as Father Luca

Eliza Stella Mason as Cathleen, 7 Years Old

Bill Shick as Local Priest

Danny Vinson as Rob, Church Usher

Angela Fox as Sister Gloria

Neva Howell as Sister Eleanor

Sasha Mason as Cathleen, 12 Years Old

Peggy Walton-Walker as Nun Teacher

Ashley Bell as Sister Margaret

Rosemary Brown as Miss Williams

Gabe Beutel-Gunn as Nora's Boyfriend

Marshall Chapman as Sister Louisa

Lacy Hartselle as Sister Theresa (uncredited)

Kamryn Boyd as Blessed Sorrows Student (uncredited)

Adele Marie Pomerenke as Cathleen's Sister (uncredited)

Darla Pelton-Perez as Parent (uncredited)

Cecilia Wyle as Professed Nun (uncredited)

Joseph Wilson as Churchgoer (uncredited)

Anna Swiney as Blessed Sorrow's Student (uncredited)

Sydney Hoover as Blessed Sorrows Student (uncredited)

Kalista Dwyer as Cathleen's Sister (uncredited)

Julia Leigh as Blessed Sorrows Student (uncredited)

Laurie Pallotta as Professed Nun (uncredited)

Kaitlyn Williams as Cathleen's Sister (uncredited)

Melissa Nyenhuis as Wedding attendee (uncredited)

Rachel Mae Moore as Cathleen's Sister (uncredited)

Jeromy Nichols as Churchgoer (uncredited)

Abram Knott as Alter Boy (uncredited)

Gabriela Contaldo as Nun (uncredited)

Nettie Kraft as Friend of Noras' (uncredited)

Juliana Dougherty as Blessed Sorrows Student (uncredited)

Sydney Harris as Blessed Sorrows Student (uncredited)

Jordan Price as Blessed Sorrows Student (uncredited)

Kirk H. Andersen as Churchgoer (uncredited)

Ashley Hargrove as Cathleen Sister Nun (uncredited)

Monty Powers as Parent of Nun (uncredited)

Jeffrey Wilkerson as Church Goer (uncredited)

Courtney Cook as 2nd Year Novice Nun 1 (uncredited)

Kerry Graul as Churchgoer (uncredited)

Jenny Revord as Professed Nun (uncredited)

Bryan Fields as Church Goer (uncredited)

David Alan Spodeck as Sister Evelyn's father (uncredited)

Kurstan Buck as Student (uncredited)

Tallie Fausnaught as Cathleen's Sister (uncredited)

Robert Happy Allen as Church Dad (uncredited)

Shelton Tison as Altar Boy (uncredited)

Carter Stewart as Cathleen's Son (uncredited)

Kadence Riggs as Churchgoer (uncredited)

Valeigh Rhiannon Alford as Catholic School Girl (uncredited)

Kylie Knott as Blessed Sorrows Student (uncredited)

Abby Harkins as Professed Nun (uncredited)

Jasmin Maya Larsen as Blessed Sorrows Student (uncredited)

Stephanie Heuer as Sister Evelyn's Mom (uncredited)

Debbie Swierk as Blessed Sorrows Nun (uncredited)

Tonya Webb as Parent / Churchgoer (uncredited)

Shelby Johnson as 2nd Year Novice 2 (uncredited)

Emma Barberi as Blessed Sorrows Student (uncredited)

Shayna-Raye Funderburk as Cathleen's Sister (uncredited)

Emma Grace Peper as Blessed Sorrows Student (uncredited)

Victoria Bradford as Novice Nun (uncredited)

Phillip Trammel as Novitiate Parent (uncredited)

Kerry Graul as Church Attendee