John Ireland as John Howard Barrington

Mercedes McCambridge as Connie Carter

James Barton as Ezra Thompson

Emlyn Williams as Dr. David Dunbar

Lloyd Gough as Asylum Dr. Gordon

Basil Ruysdael as Cyrus Barrington

David Bauer as Level Louie

Harry Shannon as Asylum Warden Anderson

Celia Lovsky as Mrs. Cyrus Barrington

David McMahon as State Trooper

Chubby Johnson as Feed Store Manager

Frank Jenks as Tom, Drunk Cowboy

Emmett Lynn as Jack, Waiter

Dick Wessel as Sid, Drunk Cowboy

Frank Jaquet as Town Sheriff

Lyle Talbot as City Detective

King Donovan as Piano Player

O.Z. Whitehead as Whoopie

Frank Richards as Gargantua

Sue Casey as Miss Dean, Receptionist

Iris Adrian as Floozy at Level Louie's Place

Richard Alexander as Barfly

Barry Brooks as Hospital Prison Guard

John Frederick as Deputy

Frank Hagney as Floozy's Boyfriend

Tom Kennedy as Asylum Inmate

Paul Kruger as Police Detective