Allie Gallerani as Isabel Porter

James Franco as Dr. Cairn

Joe Pease as Roderick Porter

Scott Haze as Gunther

Lori Singer as Madame Werner

Amber Viera as Margaret

Val Lauren as Dr. Jacobs

Zoë Bleu Sidel as Lucy

Gabrielle Haugh as Allison

Pamela Anderson as Ann Williams

Cynthia Murell as Clara Barnes

Tim Blake Nelson as Dr. Lemelle

Eric Roberts as Dr. Torrington

Josh Duhamel as Detective

Carmen Argenziano as Apothecary

Dominic Rains as Mr. Baxter

Robyn Cohen as Nurse Mary Beth

Ben Youcef as Arthur Turner

Melissa Bolona as Trudy

Tamzin Brown as Nurse Oaks

Bella Popa as Emily Turner

Nina Ljeti as Marie

Anthony Mordente as Judge

Jessica Starr Folger as Rose

Nana Ghana as Rebecka

Rachel Scorpio as Belinda

Bianca Rusu as Sara

Zola Vanessa Hauge as Server

Grainne McDermott as Scantily Clad Waitress

Vincent Alvas as Vincent's Assistant

Lidiya Korotko as The Aristocrat

Tina Masafret as Aristocrat

Jeff Vernon as Aconite

Lauren B. Mosley as Aconite

Elena Cristiean as Aconite

Mary O'Connor as Pit Girl

Krista West as Pit Girl

Ciena Rae Nelson as Pit Girl

Jeannine Corcoran as Pit Girl

Laura Burnett as Rich Woman

Erin Johnson as Mrs. Baxter

Steve Koss as Aconite

Luke Loving as Male Nurse

Stacy Newton as Pit Girl

Crystal Perez as Aconite

Elvira Safiulina as Nurse

Oliver Stafford as Judge

Makena Tolman as Aconite

Loren Vea as Rich Woman

Roy James Wilson as Correction Officer Jim

Sue Wishengrad as Aconite

Topher Grace as Vincent (scene cut)