Shelley Duvall as Mildred "Millie" Lammoreaux

Sissy Spacek as Mildred "Pinky" Rose

Janice Rule as Willie Hart

Robert Fortier as Edgar Hart

Ruth Nelson as Mrs. Rose

John Cromwell as Mr. Rose

Sierra Pecheur as Ms. Bunweill

Craig Richard Nelson as Doctor Maas

Maysie Hoy as Doris

Belita Moreno as Alcira

Leslie Ann Hudson as Polly

Patricia Ann Hudson as Peggy

Beverly Ross as Deirdre Black

John Davey as Doctor Norton

Carmen Baptiste as Rehab Patient (uncredited)

Mary Carver as Nurse (uncredited)

Dennis Christopher as Soda Delivery Boy (uncredited)

Barrie Youngfellow as Nurse Connie (uncredited)

Bo Byers as Policeman #1 (uncredited)