Thomas Solivérès as Spirou

Alex Lutz as Fantasio

Ramzy Bedia as Zorglub

Géraldine Nakache as Seccotine

Christian Clavier as Comte de Champignac

Charlotte Gabris as Marie

Vincent Desagnat as Claude, le frère jumeau de Marie

Monsieur Poulpe as Un balayeur

Mark Grosy as Teddy

Caroline Tillette as L'attachée de presse

Gunther Love as Le stagiaire

Marc Bret as Assistant conciergerie

Soraya Garlenq as Vigile portique N°2

Agnès Croutelle as Femme à la montre

Grégoire Oestermann as Lambert

Jim Adhi Limas as Savant japonais (as Jim-Adhi Limas)

Julien Sibre as Assistant scientifique

Philippe Pillavoine as Volontaire