Uma Thurman as Jenny Johnson

Luke Wilson as Matt Saunders

Anna Faris as Hannah

Eddie Izzard as Professor Bedlam

Rainn Wilson as Vaughn Haige

Stelio Savante as Leo

Mike Iorio as Lenny

Wanda Sykes as Carla Dunkirk

Margaret Anne Florence as Bartender

Catherine Reitman as TV News Reporter

Tara Thompson as Young Jenny

Angel Sing as Asian Businessman

Mark Consuelos as Steve Velard

Kevin Townley as Young Barry

Eva Veronika as Elderly Lady

Lawrence Feeney as Scary Dude

Lou Bonacki as Parking Lot Manager

Jeff Norris as NYPD Officer at Garage

Greg Northrop as NYPD Officer at Station

Fallon Brooking as Young Girl

Richard Brevard as Thief

Ron Moreno as Thief

Peter Patrikios as Thief

Lillian Lynn as Pedestrian at Robbery

Traver Rains as Traver Rains

Richie Rich as Richie Rich

Emily Girvin as Bride

Abraham Sparrow as Businessman

Clem Cheung as Asian Businessman

Clint Chin as Asian Businessman

Ben Wang as Asian Businessman

Tara DiGiore as Cheerleader

Tiffany Haupt as Cheerleader

Edwin Freeman as NYPD Officer at Station