Anna Paquin as Lisa Cohen

J. Smith-Cameron as Joan Cohen

Mark Ruffalo as Gerald Maretti

Jeannie Berlin as Emily Smith

Jean Reno as Ramon Cameron

John Gallagher Jr. as Darren Rodifer

Allison Janney as Monica Patterson

Kieran Culkin as Paul Hirsch

Cyrus Hernstadt as Curtis

Matt Damon as Aaron Caije

Matthew Bush as Kurt

Rosemarie DeWitt as Mrs. Maretti

Matthew Broderick as John Andrew van Tassel

Olivia Thirlby as Monica Sloane

Kenneth Lonergan as Karl

Josh Hamilton as Victor

Stephen Adly Guirgis as Det. Mitchell

Betsy Aidem as Abigail

Sarah Steele as Becky

Adam Rose as Anthony

Nick Grodin as Matthew

Jonathan Hadary as Russell Deutsch

Glenn Fleshler as 1st Man

Michael Ealy as Dave the Lawyer

Stephen Conrad Moore as 2nd Man

Gio Perez as Kid

Jake O'Connor as David

David Mazzucchi as Lionel

Jerry Matz as Mr. Klein

Kevin Carroll as Mr. Lewis

Hina Abdullah as Angie

Enid Graham as Bonnie

Brittany Underwood as Leslie

T. Scott Cunningham as Gary

Renée Fleming as Opera Singer

Susan Graham as Opera Singer 2

Adam LeFevre as Rob

Krysten Ritter as Shopgirl

Anna Berger as Neighborhood Lady #1

Rose Arrick as Neighborhood Lady #2

Pippen Parker as Opera Fan

Stephanie Cannon as Woman Mourner #1

Kevin Geer as AIG Detective #2

Kelly Wolf as Annette

Johann Carlo as Neighbor

Carlo Alban as Rodrigo

Christine Goerke as Opera Singer "Norma"

Jason Pendergraft as Young Cop (Not Photographed)

Yves Abel as "Hoffman" Conductor

Liza Colón-Zayas as Nurse

Matt Bush as Kurt