Gugu Mbatha-Raw as Abbie

Michiel Huisman as Sam

Steve Coogan as Mitch

Timothy Simons as Dominic

Jacki Weaver as Estelle

Kate McKinnon as Glass Half Full Kate

Christopher Walken as Myron

Zach Cherry as Jim

Jessie Ennis as Melanie

Glenn Fleshler as Mean Phil

Zabryna Guevara as Dr. Michaelson

Brian Tyree Henry as Benji

Rick Holmes as Dr. Kessler

Alanna Masterson as Sally

Gayle Rankin as Mira

Erin Richards as Amber

Tami Sagher as Meryl

Tamara Tunie as Jane

Merritt Wever as Mindy

Alyssa Cheatham as Young Abbie

Celeste O'Connor as Teen Abbie

Zachary Hernandez as Young Sam

Sawyer Barth as Teen Sam

Michael Gaston as Crochet Master

Angelo Anthony Pizza as Blonde Kid

Vanessa Carrasco as Naughty Kid

Edan Alexander as Cute Little Kid

Alexa Tropper as Awkward Girl

Grace Rex as Interviewee