Casey Affleck as Robert Ford

Brad Pitt as Jesse James

Sam Rockwell as Charley Ford

Paul Schneider as Dick Liddil

Jeremy Renner as Wood Hite

Garret Dillahunt as Ed Miller

Sam Shepard as Frank James

Mary-Louise Parker as Zee James

Zooey Deschanel as Dorothy Evans

Ted Levine as Sheriff Timberlake

Michael Parks as Henry Craig

Alison Elliott as Martha Bolton

James Carville as Governor Crittenden

Tom Aldredge as Major George Hite

Hugh Ross as Narrator (voice)

Brooklynn Proulx as Mary James

Dustin Bollinger as Tim James

Joel McNichol as Express Messenger

James Defelice as Baggagemaster

J.C. Roberts as Engineer

Darrell Orydzuk as Ukrainian Train Passenger

Jonathan Erich Drachenberg as Young Train Passenger

Torben S. Hansen as Danish Train Passenger

Lauren Calvert as Ida

Kailin See as Sarah Hite

Jesse Frechette as Albert Ford

Pat Healy as Wilbur Ford

Joel Duncan as Deputy

Stephanie Wahlstrom as Store Customer

Adam Arlukiewicz as Newsboy

Ian Ferrier as Photographer

Michael J Rogers as Onlooker at Jesse's Death

Calvin Bliid as Small Boy at Jesse's Death

Sarah Lind as Bob's Girlfriend

Nick Cave as Bowery Saloon Singer

Matthew Walker as Bowery Saloonkeeper

Michael Copeman as Edward O'Kelly

Laryssa Yanchak as Ella Mae Waterson

Anthony Harrison as Marshal Craig (uncredited)