Alain Chabat as Santa

Golshifteh Farahani as Amélie

Audrey Tautou as Wanda

Pio Marmaï as Thomas

Bruno Sanches as Magnus

David Marsais as Inspecteur Olivier Le Guennec

Grégoire Ludig as Commissaire Stéphane Bertoli

Johann Dionnet as Jay

Louise Chabat as Lutine

Eléna Plonka as Tatyana

Mark Grosy as Pharmacien

Kyan Khojandi as Le frère d'Amélie

Tara Lugassy as Maëlle

Simon Aouizerate as Mathis

Jean-Pierre Bacri as Le Père Noël rouge et blanc

Mark Grosy as Le pharmacien

Audrey Giacomini as La pharmacienne

Ambre Larrazet as La fliquette

Stella Rocha as Gisèle / Gustavo

Xing Xing Cheng as La grand-mère chinoise

Sissi Duparc as Collègue Amélie Rungis

Nicolas Lumbreras as Le poissonnier

Paloma Coquant as Barmaid Rungis

Yann Frisch as Pilier comptoir Rungis

Ian Fenelon as Pilier comptoir Rungis

Gérard Graillot as Pilier comptoir Rungis

Véronica Novak as Barbara

Thomas VDB as Le dealer de blagues cauchemar

Charline Paul as Evil Lutine mais gentille quand même

Zaven Najjar as Membre famille Amélie