John Barrymore as Svengali

Marian Marsh as Trilby O'Farrell

Donald Crisp as The Laird

Bramwell Fletcher as Billee

Carmel Myers as Madame Honori

Luis Alberni as Gecko

Lumsden Hare as Monsieur Taffy

Paul Porcasi as Bonelli

Ferike Boros as Marta (uncredited)

Adrienne D'Ambricourt as Mme. Vinard (uncredited)

Yola d'Avril as Maid (uncredited)

Rose Dione as Trilby's Mother (uncredited)