Lupita Nyong'o as Adelaide Wilson / Red

Winston Duke as Gabe Wilson / Abraham

Elisabeth Moss as Kitty Tyler / Dahlia

Tim Heidecker as Josh Tyler / Tex

Shahadi Wright Joseph as Zora Wilson / Umbrae

Evan Alex as Jason Wilson / Pluto

Yahya Abdul-Mateen II as Russell Thomas / Weyland

Anna Diop as Rayne Thomas / Eartha

Cali Sheldon as Becca Tyler / Io

Noelle Sheldon as Lindsey Tyler / Nix

Madison Curry as Young Adelaide Wilson / Young Red

Ashley McKoy as Teenage Adelaide Wilson / Teenage Red

Napiera Groves as Dr. Foster

Lon Gowan as Don

Alan Frazier as Ferdie / Jeremiah

Duke Nicholson as Danny / Tony

Dustin Ybarra as Troy / Brand

Nathan Harrington as Glen / Jack

Kara Hayward as Nancy / Syd

Jordan Peele as Dying Rabbit / Fun House Narrator (voice) (uncredited)

Darrel Cherney as News Anchor (uncredited)

James Cobb as Don (uncredited)

Alessandro Garcia as EMT (uncredited)

David M Sandoval Jr. as Father of Family on Beach (uncredited)