Warren Hull as Mandrake the Magician

Doris Weston as Betty Houston

Al Kikume as Lothar, Mandrake's Assistant

Rex Downing as Tommy Houston

Edward Earle as Dr. Andre Bennett

Forbes Murray as Professor Houston

Kenneth MacDonald as James Webster

Don Beddoe as Frank Raymond

Dick Curtis as Dorgan - Thug (Chs. 6-8)

John Tyrrell as Dirk, lead thug

Stanley Brown as Green, thug [Chs. 1, 2, 4]

Beatrice Curtis as Rest Home Nurse [Chs. 3,10]

Robert Sterling as Henchman

Sam Ash as George Regan, hypnotist [Chs. 3-5]

Lester Dorr as Gray, gas station thug [Chs. 8-9]