Claire Foy as Sawyer Valentini

Joshua Leonard as David Strine

Jay Pharoah as Nate Hoffman

Juno Temple as Violet

Aimee Mullins as Ashley Brighterhouse

Amy Irving as Angela Valentini

Sarah Stiles as Jill

Marc Kudisch as Bank Manager

Colin Woodell as Mark

Myra Lucretia Taylor as Counselor

Lynda Mauze as Dolores

Zach Cherry as Dennis

Polly McKie as Nurse Boles

Raúl Castillo as Jacob

Michael Mihm as Steve

Robert Kelly as Steve's Partner

Natalie Gold as Female Patient

Sol Marina Crespo as Female Patient

Will Brill as Male Patient

Steven Maier as Male Patient

Matthew R. Staley as Medical Technician

Matt Mancini as Medical Technician

Emily Happe as Friendly Nurse

Gibson Frazier as Dr. Hawthorne

Erin Wilhelmi as Hayley

Joseph P. Reidy as Lawyer

Matt Damon as Detective Ferguson

Erika Rolfsrud as Medical Examiner

Elizabeth Goodman as TruthBite Editor

Roshanna Jenkins as Federal Agent

Lance Coughlin as Police Officer (uncredited)

Kevin Dean O'Connor as George Shaw (uncredited)

Arthur Shaffer as FBI Agent (uncredited)

Ursula Triplett as Arresting Police Officer (uncredited)