Anthony Ramos as Usnavi

Corey Hawkins as Benny

Leslie Grace as Nina Rosario

Melissa Barrera as Vanessa

Olga Merediz as Abuela Claudia

Daphne Rubin-Vega as Daniela

Gregory Diaz IV as Sonny

Marc Anthony as Gapo

Jimmy Smits as Kevin Rosario

Stephanie Beatriz as Carla

Dascha Polanco as Cuca

Noah Catala as Graffiti Pete

Lin-Manuel Miranda as Piragüero

Mateo Gómez as Alejandro

Patrick Page as Pike

Olivia Perez as Iris

Analia Gomez as Rosa

Dean Scott Vazquez as Sedo

Mason Vazquez as Miggy

Delila Ramos as Cranky Vieja

Valentina as Self

Christopher Jackson as Mr. Softee Truck Driver

Susan Pourfar as Hannah Hathaway

María Hinojosa as Protest Leader

Ryan Woodle as Mover

Doreen Montalvo as Neighbor Lady

Ilia Jessica Castro as Jessica from the Salon

Yesy Garcia as Woman in Lobby

Jonathan Arana as Salon Customer

Jennifer Hernandez as Bad-Ass Girl

Amp Ngernrungruangroj as Hipster

Bairam Rizai as Young Professional Couple

Lavinia Jones Wright as Young Professional Couple

Alexandra Campos as Cab Service Dispatcher

Rhapsody James as Salon Customer 1

Ariana S. Gomez as Young Nina

Ariana Greenblatt as Young Nina

Hugh M Jones III as Man Washing Car

Luis A. Miranda Jr. as Man in Street (uncredited)

Javier Muñoz as Man in Street (uncredited)

The Kid Mero as DJ (voice) (uncredited)

Seth Stewart as Bartender (uncredited)