Oscar Isaac as Gomez Addams (voice)

Charlize Theron as Morticia Addams (voice)

Chloë Grace Moretz as Wednesday Addams (voice)

Finn Wolfhard as Pugsley Addams (voice)

Nick Kroll as Uncle Fester (voice)

Snoop Dogg as Cousin Itt (voice)

Bette Midler as Grandma (voice)

Allison Janney as Margaux Needler (voice)

Martin Short as Grandpa Frump (voice)

Catherine O'Hara as Grandma Frump (voice)

Tituss Burgess as Glenn (voice)

Jenifer Lewis as Great Auntie Sloom (Voice)

Elsie Fisher as Parker Needler (voice)

Conrad Vernon as Lurch / Priest / Spirit of the House / Dr. Flambe (voice)

Aimee Garcia as Denise (voice)

Scott Underwood as Mitch (voice)

Mikey Madison as Candi the Barista (voice)

Chelsea Frei as Bethany (voice)

Pom Klementieff as Layla & Kayla (voice)

Deven Green as Ms. Gravely (voice)

Maggie Wheeler as Trudy Pickering (voice)

Harland Williams as Norman Pickering / Ggerri (voice)