Carla Gugino as Cathy Rush

Marley Shelton as Sister Sunday

Ellen Burstyn as Mother St. John

David Boreanaz as Ed Rush

Katie Hayek as Trish Sharkey

Kim Blair as Lizanne Caufield

Meghan Sabia as Jen Galentino

Margaret Anne Florence as Rosemary Keenan

Kate Nowlin as Colleen McCann

Taylor Steel as Mimi Malone

Bianca Brunson as Gayle Moore

Malachy McCourt as Monsignor

Phyllis Somerville as Sister Sister

Jodie Lynne McClintock as Sister Thomas

Marianne Bonner as Sister Sarge

Ginny Graham as Sister Jane

Lauren Bittner as Mary Margaret O'Malley

Lauren Karl as Kelly MacDougal

Catherine Rush as Bank Teller

Ed T. Rush as Sidewalk Patron

Mike Burns as Young Priest

John Peakes as Harry McHale

Robert Michael Kelly as Board Member

Donald Cairns as Board Member

David Howey as Photographer

Ward Horton as Frankie Sharkey

Joanne Bradley as West Chester Coach

Katie Davis as Immaculata Reserve

Matt Chambers as Basketball player

Paul Chambers as Basketball player

Paul M. Chambers as Basketball player

J.P. Dunphy as Basketball player

Patrick Traver as Basketball player

Sean Pratt as Jimmy Sullivan

Erin Mosher as Mrs. Sullivan

Brooke Josephson as Mrs. Kincade

Jesse Draper as Mrs. Ballard

Tom McCarthy as Foot Lotion Buyer

Kendal Ridgeway as Marian Sharkey

Tisha Tinsman as Rita Galentino

Tony Luke Jr. as Salvatore Galentino

Brandon Hannan as Tony Galentino

Christopher Mann as Julius Moore

Tess Roney as Joanne Caufield

Maggie Kincade as Megan Caufield

Josh Green as Cowboy in bar

Kathy Romano as Flight Attendant

William R. Johnson as LaSalle Athletic Director

Pete Postiglione as Security Guard

Michael Smerconish as Reporter #1

Anthony Gargano as Reporter #2

Joe Conklin as Announcer

Regina Murphy as Referee

Lisa Ballard as Referee

Kristin Schupp as Referee

Carolyn Longenderfer as Waitress

Jennifer Meehan as Woman in Bathroom

Courtney Mix as South Dakota State Player

Tim Sherry as Bartender

Patrick McDade as Cupcake Buyer

Richard Alliger as Security Guard

Ruthie Bolton as Mississippi State Coach

Evan Bochetto as Locker Room Assistant

Jacob D'Orazio as Program Seller

Tolly Sherry as Cheerleading Nun

Kim Johnson as Cheerleading Nun

Andrea Strang as Cheerleading Nun

Sharon Dacey as Cheerleading Nun

Victoria Guinta as Cheerleading Nun

Trudy Wilson as Cheerleading Nun

Francine Bianco Tax as Cheerleader Nun

Gina Allegro as Rosemont Coach (uncredited)

Vale Anoai as College Student in Church (uncredited)

Robert Bizik as Basketball Fan (uncredited)

Sara Jane Blazo as West Chester Asst Coach (uncredited)

Michael Edward Brooks as Basketball fan (uncredited)

David E. Brown as Basketball Referee (uncredited)

Frank Aptacy as Bar Patron (uncredited)

Gary Beck as Student Fan (uncredited)

Rich Bryant as Immaculata Student (uncredited)

Jennifer Butler as Nun (uncredited)

Alice Chamberlain as Nun (uncredited)

Karen Chamberlain as Nun (uncredited)

Judy Corona-Karpowicz as Basketball Fan (uncredited)

Sarah Donaldson as Core Group Student (uncredited)

Mary Ellen Driscoll as Assistant Coach, Mississippi State (uncredited)

Cindy Engle as Faculty / Fan (uncredited)

Evangeline as College Student (uncredited)

Erich Ficke as Basketball Patron (uncredited)

Erin Frederick as Immaculata Student (uncredited)

Leslie Noel Haigh as Drummer Girl (uncredited)

Kim Handloff as College Student / Nun (uncredited)

Basil Kershner as Basketball Fan (uncredited)

Steven J. Klaszky as Scorekeeper (uncredited)

Kathleen LaGue as Voices (uncredited)

Traci Law as Student in Stands (uncredited)

Erin Lulevitch as Student (uncredited)

Fallon Maressa as Student (uncredited)

Jeffrey Mowery as Fan in Pheasant Pants (uncredited)

Keith Moyer as Biker (uncredited)

Ken Myers as Fan (uncredited)

Chelsea O'Toole as Nun (uncredited)

Jean Orlando as Nun (uncredited)

Charles Pendelton as Cab Driver / Featured (uncredited)

Janine Rafalko as College Student (uncredited)

Vincent Riviezzo as Bank Customer (uncredited)

Shawnee Robertson as Cheering Nun (uncredited)

John Roney as Thomas Caufield (uncredited)

Megan Rose as Catholic school girl (uncredited)

Mark Savage Jr. as Fan (uncredited)

Chuck Schanamann as Charlie Malone (uncredited)

Mark Schroeder as Scorekeeper #2 (uncredited)

Mark Simms as Fan (uncredited)

Danielle Stoner as Parishoner (uncredited)

Ryan Tygh as Sporting Goods Stock Boy (uncredited)

Dan Van Wert as Basketball Fan (uncredited)

Diane Varrenti as Friend of the Family (uncredited)

Sonny Vellozzi as Scorekeeper (uncredited)

Kimberly Villanova as Nun (uncredited)

Ryan Windish as Monsignor Assistant (uncredited)

Scott Yannick as Stadium Security Guard (uncredited)