Jeremy Renner as Aaron Cross

Rachel Weisz as Dr. Marta Shearing

Edward Norton as Byer

Stacy Keach as Turso

Dennis Boutsikaris as Ward

Oscar Isaac as Outcome #3

Joan Allen as Pamela Landy

Albert Finney as Dr. Albert Hirsch

David Strathairn as Noah Vosen

Scott Glenn as Ezra Kramer

Donna Murphy as Dita Mandy

Michael Chernus as Arthur Ingram

Corey Stoll as Vendel

Zeljko Ivanek as Dr. Donald Foite

Shane Jacobson as Mackie

Elizabeth Marvel as Dr. Connie Dowd

John Douglas Thompson as Lt. Gen. Paulsen

Louis Ozawa as LARX #3

David Wilson Barnes as Drone Spec

Neil Brooks Cunningham as Dr. Dan Hillcott

Corey Johnson as Ray Wills

Michael Berresse as Leonard

Alice Gainer as Lean Forward MSNBC Anchor

Prue Lewarne as CNN Reporter

Howard Leader as MSNBC Analyst

James Joseph O'Neil as Sterisyn-Morlanta Gateman

Tony Guida as Dr. Benezara

Sonnie Brown as Dr. Lieberburg

Robert Christopher Riley as Outcome #6

Noel Wilson as Neuro Luncheon MC

Jennifer Kim as Outcome #4

Page Leong as Mrs. Yun

Adi Hanash as Outcome #1

Robert Prescott as Air Force Officer

Don Guillory as Drone Pilot

Patrick Vincent Marro as Drone Command Guard

Ali Reza as Dr. Talwar

Gita Reddy as Dr. Chandra

Tom Riis Farrell as Blue Lab Doctor

Steve Routman as Blue Lab Doctor

Peter Gray Lewis as Blue Lab Doctor

Anitha Gandhi as Blue Lab Doctor

Heather Rasche as Blue Lab Doctor

Natalie Bird as Blue Lab Doctor

Nilaja Sun as Blue Lab Doctor

Christopher Mann as Lab Guard

Billy Smith as Lab Guard

Murray Knudsen as Alaska Airport Guard

Susan Egbert as DIA Attorney

Tim Devitt as FBI Honcho

Brian Poteat as State Investigator

Clayton J. Barber as Gene

Michael Papajohn as Larry Hooper

David Leitch as The Driver

Deidre Goodwin as Candent Spokesperson

Laura Spaeth as Walking Woman

Sam Gilroy as C-Team

Rachel Black as C-Team

Sharon Washington as C-Team

Frank Deal as C-Team

Rob Yang as C-Team

Catherine Curtin as C-Team

Matt Oberg as C-Team

Gary Lee Mahmoud as C-Team

Faye Yvette McQueen as TSA Guard

Pat Battle as MSNBC Anchor

Nico Bernuth as Flight Attendant

Jane Jameston as Flight Attendant

Roland Manansala as Steri-M Guard

John Arcilla as Joseph

Josh Banks as Mackie's Assistant

Allen Jo as Guard

Jonathan Eusebio as Guard

Jon Valera as Guard

Carl Villa Roman as Sterival Catwalk Guard

Madeleine Nicolas as Landlady

Ruby Ruiz as Philippine Pharmacist

Cherry Devera as Crisis Translator

Julienne Orindain as TV Girl

Antonette Garcia as TV Mom

Sonny Tuazon as Manila Cop

Normandy Bacaltos as Manila Cop

Edgar Letran as Manila Cop

Alvin Zalamea as Manila Cop

Spencer Sano as Manila Cop

Julie Ysla as Woman with the Bag

Joel Torre as Citrus Samaritan

Ermie Concepcion as Pissed Off Guy

Arthur Acuña as Manila Driver

Adrian Talinga as Captain's Son

Lou Veloso as Captain

Ian Blackman as Landy's Attorney

Jodi Applegate Kay as Landy Reporter

Tony Carlin as Landy Reporter

Karen Pittman as Landy Reporter

Ana Berry as Landy Reporter

Matthew J. Walters as Landy Reporter

Brian O'Neill as Landy Reporter

Paddy Considine as Simon Ross (archive footage) (uncredited)

Sheena Colette as Candent Woman #2 (uncredited)

Alexis Molnar as Hotel Teen Girl (uncredited)

Courtney Hart as Market Shopper (uncredited)