Willem Dafoe as Vincent van Gogh

Rupert Friend as Theo van Gogh

Oscar Isaac as Paul Gauguin

Mads Mikkelsen as The Priest

Mathieu Amalric as Dr. Paul Gachet

Emmanuelle Seigner as Madame Ginoux

Niels Arestrup as Madman

Anne Consigny as Teacher

Amira Casar as Johanna van Gogh-Bonger

Vincent Perez as The Director

Lolita Chammah as Girl on the Road

Stella Schnabel as Gaby

Alexis Michalik as Artists Tambourin

Vladimir Consigny as Doctor Felix Ray

Arthur Jacquin as René

Solal Forte as Gaston

Vincent Grass as Café Owner

Clément Lhuaire as Emile Bernard

Alan Aubert-Carlin as Albert Aurier / Painter

Laurent Bateau as Joseph Roulin

Frank Molinaro as Henri de Toulouse-Lautrec

Montassar Alaya as Zouave

Didier Jarre as Asylum Guard

Thierry Nenez as Clerk Hôtel de la Gare

Johan Kugelberg as Surgeon

François Delaive as Artists Tambourin

Nicolas Abraham as Artists Tambourin

Manuel Guillot as Artists Tambourin

Paul Théotime as School Child

Romane Libert as School Child

Milo Aubriet as School Child

Clélia Robin-Oeustreicher as School Child

Arthur Gloanec as School Child

Alfred Boch as School Child

Ludmilla Roitbourd as School Child

Louis Garrel as Aurier's Article (voice)

Victor Pontecorvo as Farmer's Son (uncredited)