George Clooney as Jimmy 'Dodge' Connelly

Renée Zellweger as Lexie Littleton

John Krasinski as Carter Rutherford

Wayne Duvall as Coach Frank Ferguson

Stephen Root as Suds

Jonathan Pryce as CC Frazier

Jack Thompson as Harvey

Max Casella as Mack Steiner

Matt Bushell as Curly

Nick Paonessa as Zoom

Malcolm Goodwin as Bakes

Robert Baker as Stump

Tim Griffin as Ralph

Keith Loneker as Big Gus

David de Vries as Princeton Reporter

Rick Forrester as Princeton Reporter

Tommy Hinkley as Hardleg

Lance Barber as Toledo Referee

Nicholas Bourdages as Bug

Jason Drago as Toledo Player

Bill Roberson as Mr. Dunn

Hi Bedford-Roberson as Mrs. Dunn

Mark Teich as Joe

Christian Stolte as Pete

Windy Wenderlich as Conductor

Marian Seldes as Clerk

Thomas Francis Murphy as Cook

JD Cullum as Leonard

Dave Hager as Duluth Reporter

Danny Vinson as Duluth Reporter

Mike O'Malley as Mickey

Dylan Kussman as Soldier Frank

Ryan Shively as Corporal Jack

Kyle Nudo as German Soldier

Heather Goldenhersh as Belinda / Flapper

Grant Heslov as Saul Keller

Bobby Jordan as Football Player (uncredited)