Andy On as Black Mask / Kan Fung

Tobin Bell as Moloch

Jon Polito as King

Teresa Maria Herrera as Dr. Marco Leung

Scott Adkins as Dr. Lang

Rob Szatkowski as Claw

Tyler Mane as Thorn

Oris Erhuero as Wolf

Sean Marquette as Raymond

Robert Allen Mukes as Snake

Michael Bailey Smith as Ross

Andrew Bryniarski as Iguana

Traci Lords as Chameleon

Blackie Ko as Inspector

Silvio Simac as General Troy

Terence Yin Chi-Wai as Dr. David

Marcus Fox as Thai Policeman

Cherrie Ying Choi-Yi as (Voice)

Louis Koo as (Voice)