Jeff Bridges as Roy Pulsipher

Ryan Reynolds as Nick Walker

Kevin Bacon as Bobby Hayes

Mary-Louise Parker as Proctor

Stephanie Szostak as Julia

Robert Knepper as Nawlicki

James Hong as Nick's Avatar / Jerry Chen

Marisa Miller as Roy's Avatar

Mike O'Malley as Elliot

Devin Ratray as Pulaski

Larry Joe Campbell as Murphy

Michael Coons as Detective in Locker Room

Chris Everett as R.I.P.D. Evidence Clerk

Michael Tow as R.I.P.D. Evidence Clerk

Lonnie Farmer as Proctor's Avatar

Piper Mackenzie Harris as Nick's New Avatar

Ben Sloane as Clerk in VCR Repair Shop

Duncan B. Putney as Executive

Bill Mootos as Executive

Kortney Adams as Office Girl

Michael Yebba as Jersey Deado

David J. Curtis as Multi-Armed Deado

Kachina Dechert as Goth Chick

Cheryl McMahon as Driving Deado

Georgia Lyman as Female Cop

Matt McColm as Male Cop

Catherine Kresge as Female TV Reporter

John Burke as Newscaster in Helicopter

Joe Stapleton as R.I.P.D. '70s Cop

Michael Steven Costello as R.I.P.D. Cop

Naheem Garcia as R.I.P.D. Cop

Lance Greene as R.I.P.D. Cop

Tobias Segal as Clement Smokewagon Perkins

Mike Judge as Various Deado Voices (voice)

Toby Huss as Various Deado Voices (voice)

Jon Olson as Various Deado Voices (voice)

Emmalyn Anderson as Driver (uncredited)

Alexandra Creteau as Red Sox Fan (uncredited)

Jim Ford as Cop #7 (uncredited)

John Franchi as Pedestrian (uncredited)

J. Jewels as 1970's Detective (uncredited)

Chris Whitney as Deado #8 (uncredited)

D.J. 'Shangela' Pierce as Drag Queen Avatar (uncredited)