Catherine Tate as Karen Cooper

Robert Pattinson as Daniel Gale

Anne Reid as Nancy Hesketh

Holliday Grainger as Charlie Cooper

Steve Pemberton as Leo Fairbrother

Maggie Ollerenshaw as Jessie Pilkington

Oliver Lee as Paul Benthem

Clare McGlinn as Advisor Jo-Beth

Pip Torrens as Doctor Gale

Kirsty Leigh Porter as Anya

Caroline Harding as Sandra Gale

Steve John Shepherd as Steve Cooper

Angela Murray as Adviser Annie

Steve Brody as Tom

Olga Grahame as Ivy

Mary Wray as Irene Seddon

Penny Layden as Rambler Annie

Caroline O'Neill as Mary Beattie

Daryl Fishwick as Mrs Carlisle

Alison Burrows as Nurse