Bryan Cranston as Mack

Sam Rockwell as Ivan (voice)

Brooklynn Prince as Ruby (voice)

Angelina Jolie as Stella (voice)

Danny DeVito as Bob (voice)

Ariana Greenblatt as Julia

Helen Mirren as Snickers (voice)

Phillipa Soo as Thelma (voice)

Mike White as Frankie (voice) / Passing Driver

Ron Funches as Murphy (voice)

Chaka Khan as Henrietta (voice)

Ramón Rodríguez as George

Owain Arthur as Castello

Kevin Mathurin as Mike

Hannah Bourne as Helen

Betsy Graver as Mother In Park

Beckett Handley as Boy In Photo

Larry Ridley as News Reporter

Eleanor Matsuura as Candace Taylor

Kriss Dillon as Animal Inspector #1

Max Dowler as Animal Inspector #2

Indira Varma as Dr. Maya Wilson

Gary Greenham as Cage Guy

Davina Sitaram as Passerby

Filiz Fairweather as Mother With Stroller

Jacqueline Ramnarine as Woman Watching The Show

Ireland Frost as Mall Protester

Dean Phillippi Sr. as RV Camper Driver

Jude Allenby-dos Santos as Kev (Boy In Mall)

Jeffrey Crisp as Man Driving Car

Tyrone Love as Mall Cop

Sean Casey as Driver

Danny La Placa as Neighbor

Roberto Vivancos as Richard Moore

Richard J. Valentine as Mall Protester

Jeremy Oliver as Circus Visitor

Jessica Hyde as Mall Patron (voice)