Shia LaBeouf as James Lort

Lucas Hedges as Otis Lort (22 years old)

Noah Jupe as Otis Lort (12 years old)

Byron Bowers as Percy

Laura San Giacomo as Dr. Moreno

FKA twigs as Shy Girl

Natasha Lyonne as Mom

Maika Monroe as Sandra

Clifton Collins Jr. as Tom

Scar as Tiny

Martin Starr as Alec

Haylee Sanchez as Working Girl 1

Giovanni Lopes as Rehab Nurse

Dorian Brown Pham as Pam

Greta Jung as AD

Craig Stark as Craig

Graham Clarke as Bucky (TV Dad)

Kevin Dunigan as Cop

Carlos Rosendo as Carlos

Leana Chavez as Working Girl 2

Paulina Lule as Person in Car

Ben Maccabee as Loud Man

Chala Savino as Loud Woman

Debra Jones as Mama DJ

Isabel Wang as Otis' Fan

Sandra Rosko as Hug Circle (uncredited)

Kara C. Roberts as Female Jogger (uncredited)

Eli Santana as AA Member (uncredited)

Ludwig Manukian as Hotel Manager (uncredited)

Zack Whyel as Trailer Park Drunk (uncredited)

Kingston Vernes as Benny (uncredited)

Bryan Sapphire as Biker (uncredited)

Autumn Barlow as Dancer (uncredited)

Al Burke as Biker (uncredited)