Chrissy Metz as Joyce Smith

Josh Lucas as Brian Smith

Topher Grace as Pastor Jason Noble

Mike Colter as Tommy Shine

Marcel Ruiz as John Smith

Sam Trammell as Dr. Kent Sutterer

Dennis Haysbert as Dr. Garrett

Maddy Martin as Abby Sutterer

Isaac Kragten as Josh

Nikolas Dukic as Reiger

Taylor Mosby as Chayla

Alissa Skovbye as Emma

Chuck Shamata as Chief Marlo

Nancy Sorel as Mrs. Abbott

Lisa Durupt as Paula Noble

Rebecca Staab as Cindy Reiger

Victor Zinck, Jr. as Joe Marrow

Kristen Harris as Kay Quinn

Stephanie Czajkowski as Melissa

Mel Marginet as Trauma Room Nurse #1

Logan Creran as Luke Noble

Isla Gorton as Daughter #2

Karl Thordarson as Don

Tristan Mackid as Punk

Jemma Griffith as Doreen

Kerry Grace Tait as Joyce's friend #1

Elena Anciro as Trauma Room Nurse #2

Danielle Savage as Mom #2

Saul Elias as 7 Year Old John

Lois Brothers as E.R. Nurse

Maclean Fish as Bigger Punk

Sarah Constible as Neighbor Lady

Miriam Smith as VP Nancy Benes

Jordan Kronis as Chad Green

Danny Wattley as Coach Paul

Kate Yacula as Assistant Maddy

Annelise Pollmann as Olivia Noble

Phil Wickham as Worship Leader

Sandy Fernandez as Drummer

Rena Semenko as Keyboardist

Blair De Pape as Bass Player

Derrick Gottfried as Guitarist

Lecrae as Rob

Stella Pruse as Cathy

Robert Morgan as Bob

Cory Wojcik as Manager

Jay Koensgen as Recruit

Jeff Strome as Fire Truck Driver

Jason Wishnowski as Cop #1

Will Woytowich as Cop #2

Ryan Ash as Paramedic #1

Veronica Ternopolski as Paramedic #2

Scott Johnson as Keith

Rebekah Grenkow as Trauma Room Nurse #3

Stephanie Sy as E.R. Receptionist

Ernie Pitts as Crew Member

Beverly Ndukwu as Cardinal Glennon Nurse

Alicia Johnston as Wife (Mrs. Sutterer)

Lauren Cochrane as Nurse Wendy Hof

Erik Athavale as Dr. Lulu

Robin Ruel as Neurologist

Onalee Minuk as Mom #1

Callie Lane as Daughter #1

Phil Hepner as Mr. Reiger (uncredited)

Connor Peterson as Band Student / Student (uncredited)

Travis Bryant as Jonah (uncredited)

Kevin P. Gabel as Male Nurse (uncredited)

Geoff Banjavich as Pulmonologist (uncredited)

Scott Carnegie as EMT (uncredited)

Connor Chennells as Student (uncredited)

Chris Glenat as Saint Joseph Medical Staff (uncredited)

Craig Harrison as Hospital Worker (uncredited)

Jim Kirby as Church Member (uncredited)

Tyanne McNicoll as Church Member (uncredited)

Cindy Rose Myskiw as Cheering Crowd / Church Member (uncredited)

Steve Pacaud as Church Preacher (uncredited)

Lorrie Papadopoulos as Cheering Crowd / Church Member (uncredited)

Derek James Trapp as Police Officer (uncredited)

William Whyte as Church Congregation / Well Wisher (uncredited)

Lara Wieler as Lara Wieler - Church attendee (uncredited)

Ryan David Younes as Basketball Player (uncredited)