Amy Adams as Anna Fox

Gary Oldman as Alistair Russell

Anthony Mackie as Ed Fox

Fred Hechinger as Ethan Russell

Wyatt Russell as David Winter

Brian Tyree Henry as Detective Little

Jennifer Jason Leigh as Jane Russell 2

Jeanine Serralles as Detective Norelli

Mariah Bozeman as Olivia Fox

Julianne Moore as Jane Russell 1 (Katie)

Diane Dehn as 911 Dispatcher (voice)

Daymien Valentino as Mover

Anna Cameron as Alex (voice)

Myers Bartlett as 911 Dispatcher (voice)

Haven Burton Paschall as Shelly (voice)

Ben Davis as Steve (voice)

Blake Morris as 911 Dispatcher (voice)

Tracy Letts as Dr. Landy (uncredited)