Luis Tosar as Costa

Gael García Bernal as Sebastián

Juan Carlos Aduviri as Daniel / Hatuey

Karra Elejalde as Antón / Christopher Columbus

Raúl Arévalo as Juan / Antonio de Montesinos

Cassandra Ciangherotti as María

Carlos Santos as Alberto / Bartolomé de las Casas

Milena Soliz as Belén / Panuca

Leónidas Chiri as Teresa

Ezequiel Díaz as Bruno

Pau Cólera as Actor capitán

Vicente Romero Sánchez as Actor comandante

Antonio Mora as Actor franciscano

Daniel Currás as Soldado gallego

Glenda Rodríguez as Asistente casting

Sonia Ovando as Ona / Sonia

Jorge Ortiz as Prefecto

Luis Bredow as Comisario

Bernardo Arancibia Flores as Médico

Alejandro Lanza as Enfermera

Fernando Cervantes as Sacerdote

Oscar-Ricardo Encinas as Auxiliar de cámara

Ivan Candia as Extra

Andrea Camponovo as Make-up artist

Diego Ortiz as Guardia

Alejandra Lanza as Enfermera (uncredited)

Najwa Nimri as Isabel (uncredited)

Javier B. Suarez as Colono español (uncredited)