Dee Bradley Baker as Louie (voice)

Jason Alexander as Father (voice)

Mary Steenburgen as Mother (voice)

Reese Witherspoon as Serena (voice)

Kath Soucie as Serena (cygnet) / Paramedic / Newscaster (voice)

Carol Burnett as Mrs. Hammerbotham (voice)

Seth Green as Boyd (voice)

Joe Mantegna as Monty (voice)

Sam Gifaldi as Sam the Beaver (voice)

Melissa Disney as Billie (voice)

E. G. Daily as Ella (voice)

Pamela Adlon as A.G. Skinner (voice)

Steve Vinovich as Maurice / Roger (voice)

Gary Anthony Williams as Sweets (voice)

Corey Burton as Senator (voice)

Michael Winslow as Chief (voice)

David Jeremiah as Squirrel / Hawk (voice)

Julie Nathanson as Felicity (voice)

Jack Angel as Justice of the Geese (voice)