Halle Berry as Frankie

Stellan Skarsgård as Oz

Phylicia Rashād as Edna

Chandra Wilson as Maxine

Adrian Holmes as Cliff

Melanie Papalia as Tina

Rosalyn Coleman as Pearl

Brian Markinson as Dr. Backman

Matt Frewer as Dr. Strassfield

Sean Tyson as Rich Fat Cat

Kira Clavell as Wanda

Joey Bothwell as Trish

Katharine Isabelle as Paige

James Kirk as Bobby

Megan Charpentier as Young Paige (8 years old)

Emily Tennant as Paige (16 years old)

Alex Diakun as Hal

Joanne Baron as Nurse Susan Shaw

Kennedy Goodkey as Cop #1

Andrew Francis as Cop #2

Vanessa Morgan as Frankie (16 years old)

Kenneth W. Yanko as Judge Prescott

Scott Lyster as Pete Prescott

Anne Marie DeLuise as White Alice

Ben Cole as Robert (Groom)

Calvin Lee as Store Owner

Matias Hacker as Hector

Paul Puzzella as Polyester Molester

Eric Pollins as Bump and Grind Patron

Darryl Scheelar as Waiter

Rod Conway as Carl

Alexis Ioannidis as Celeste

Xantha Radley as Maria (Anorexic Girl)

Colin Foo as Thin Asian Patient

Christina Schild as Annabel Prescott

Kathryn Kirkpatrick as Admission Nurse

William J. Phillips as Dan

Richard Cohee as Black Janitor

L. Harvey Gold as Bar Executive #1

Troy Rudolph as Bar Executive #2

Primo Allon as Pool Player #1

Steffan Chavarria as Pool Player #2

Cheryl Adams as Code Green Nurse

Daniella Evangelista as Maria (uncredited)

Ildiko Ferenczi as Dancer (uncredited)

Sabine Mondestin as Ciff's Wife (uncredited)

Jennifer Oleksiuk as Exotic Dancer (uncredited)