Hayden Panettiere as Red Riding Hood (voice)

Glenn Close as Granny (voice)

Patrick Warburton as The Big Bad Wolf (voice)

David Ogden Stiers as Nicky Flippers (voice)

Joan Cusack as Verushka the Witch (voice)

Bill Hader as Hansel (voice)

Amy Poehler as Gretel (voice)

Cory Edwards as Twitchy (voice)

Martin Short as Kirk the Woodsman (voice)

Brad Garrett as The Giant (voice)

Andy Dick as Boingo the Bunny (voice)

David Alan Grier as Moss the Troll (voice)

Cheech Marin as Mad Hog (voice)

Tommy Chong as Stone (voice)

Phil LaMarr as Wood / Ernesto (voice)

Wayne Newton as Jimmy 10-Strings (voice)

Benjy Gaither as Japeth the Goat (voice)

Danny Pudi as Little Boy Blue (voice)

Debra Wilson as Iana (voice)

Tress MacNeille as Vera / Woman’s Voice (voice)

Heidi Klum as Heidi (voice)

Clarissa Jacobson as Flo (voice)

Mike Disa as Helmut / Spider / Rhino / HEA Agent 1 & 2 (voice)

Rob Paulsen as Johann / Bad Shatner / Bad Kelley (voice)

Lance J. Holt as Klaus (voice)

Robert Anich as Veronica Rhino (voice)

Rebecca Anderson as Radio Voice (voice)