Elizabeth Banks as Joy

Sigourney Weaver as Virginia

Chris Messina as Will

Wunmi Mosaku as Gwen

Kate Mara as Lana

Cory Michael Smith as Dean

Grace Edwards as Charlotte

John Magaro as Detective Chilmark

Aida Turturro as Sister Mike

Emily Creighton as PTO mom

Gina Jun as Reporter

Rebecca Henderson as Edie

Bianca D'Ambrosio as Erin

John Rothman as Director McDonald

Geoffrey Cantor as Dr. Falk

Evangeline Young as Maeve

Beau Baxter as Dr. Aaronson

Joel Brady as Dr. Campbell

Maia Scalia as Marion