Anton Yelchin as Charley Brewster

Colin Farrell as Jerry Dandrige

Toni Collette as Jane Brewster

David Tennant as Peter Vincent

Imogen Poots as Amy Petersen

Christopher Mintz-Plasse as Ed Thompson

Dave Franco as Mark

Reid Ewing as Ben Wegner

Will Denton as Adam

Sandra Vergara as Ginger

Emily Montague as Doris

Chris Sarandon as Jay Dee

Gracie Gillam as Bee

Chelsea Tavares as Cara

Lisa Loeb as Victoria

Brian Huskey as Rick

Mike Miller as Store Guy

Marya Beauvais as Mrs. Granada

Kent Kirkpatrick as Teacher

Arron Shiver as Cop #1

Rick A. Ortega Jr. as Cop #2

Charlie B. Brown as Doctor

Rebekah Wiggins as Passing Nurse

Eb Lottimer as Adam's Dad

Liezl Carstens as Show Nymph #1

Laura Aidan as Show Nymph #2

Alma Sisneros as Show Nymph #3

Bruce Holmes as Pyro Guy

Chris Ranney as Guard

Lovie Johnson as D.J.

Jerry G. Angelo as Guy on Dance Floor

Tait Fletcher as Nightclub Security Guy

Kevin Christopher Brown as Jerry's House Cop #1

Jesse Pickett as Jerry's House Cop #2

William H. Burton Jr. as Hulking Man

Bonnie Morgan as Vamp #1

Michelle Waterson-Gomez as Vamp #2

Paula Francis as Newscaster #1

Dave Courvoisier as Newscaster #2

Dee Bradley Baker as Jerry's Vampire Vocals (voice)