Daniel Kaluuya as Fred Hampton

LaKeith Stanfield as Bill O'Neal

Jesse Plemons as Roy Mitchell

Dominique Fishback as Deborah Johnson

Ashton Sanders as Jimmy Palmer

Algee Smith as Jake Winters

Darrell Britt-Gibson as Bobby Rush

Lil Rel Howery as Wayne

Dominique Thorne as Judy Harmon

Martin Sheen as J. Edgar Hoover

Amari Cheatom as Collins

Khris Davis as Steel

Ian Duff as Doc Satchel

Caleb Eberhardt as Bob Lee

Robert Longstreet as Leslie Carlyle

Amber Chardae Robinson as Betty Coachman

Ikechukwu Ufomadu as Walter Hicks

James Udom as Compton

Nick Fink as Fesperman

Mell Bowser as Tex

Alysia Joy Powell as Mrs. Winters

Nicholas Velez as José Cha Cha Jiménez

AJ Carr as Anthony Timmons

Tommy Lafitte as Pool Hall Bartender

Terayle Hill as George Sams

China Shavers as College Student

Crystal Lee Brown as Darlene

Graham Lutes as Alex

Jonathan Scialabba as CPD Officer

Adam Ratcliffe as Cop

RayJonaldy Rodriguez as Mexican Teen

Tyra Joy Smith as Tracy Randle

Deonte Stubbs as Dice Game Onlooker

Cliff Weissman as Hospital Cop

Tone Tank as Officer Carcetti

James Bruner as Officer Williams

Winston Haynes as Captain James Byrne

Raymond Seay as Oldest Kid

Latjuan Wells as Youngest Kid

Michael Harrity as Menard Prison Warden

Will F. Moore as Interviewer (voice)

Ken Bolden as Maître d'

Maggie Callahan as Blonde Girl

Michael Buonomo as FBI Agent

Aaron Kleiber as Agent Saunders

Brian 'Wolfman Black' Bowman as Reg

Cooper Bucha as James

Robert Forte Shannon III as Prisoner

The Lady of Rage as Lady Panther

Jermaine Fowler as Mark Clark (uncredited)

Chris Hahn as Prison Guard (uncredited)

Linda D Gaines as Female Protestor Church / Police Station (uncredited)

Samantha Seawolf as Protestor / Puerto Rican (uncredited)