Adam Driver as Cesar Catilina

Giancarlo Esposito as Mayor Cicero

Nathalie Emmanuel as Julia Cicero

Aubrey Plaza as Wow Platinum

Shia LaBeouf as Clodio Pulcher

Jon Voight as Hamilton Crassus III

Laurence Fishburne as Fundi Romaine

Talia Shire as Constance Crassus Catilina

Jason Schwartzman as Jason Zanderz

Kathryn Hunter as Teresa Cicero

Grace VanderWaal as Vesta Sweetwater

Chloe Fineman as Clodia Pulcher

James Remar as Charles Cothope

D. B. Sweeney as Commissioner Stanley Hart

Isabelle Kusman as Claudine Pulcher

Bailey Coppola as Huey Wilkes

Madeleine Gardella as Claudette Pulcher

Balthazar Getty as Aram Kazanjian

Romy Mars as Girl Reporter

Haley Sims as Sunny Hope Catilina

Dustin Hoffman as Nush 'The Fixer' Berman

Sonia Ammar as Zena The Model

Neri Oxman as Dr. Lyra Shir

AJ Caba as Balin the Fractal

Michael Mourra as Boy Assassin

Charlie Talbert as Felix the Butler

Tommy Lee Driver as General

Caroline Bloom as Cesar's Secretary

George Dillard as Bandmaster

Donald Pitts as Ringmaster

Philip Dido as Control Room Engineer

Gayle Hooker as Mrs. Gayle

James Keane as Laughing Man

Sean Hankinson as TV Newscaster

Andrew Ayala as Spanish-Speaking Protester

Ritwik Chatterjee as Mr. Singh

Kendra Stout as Servilia

Max Bojorquez as Non English-Speaking Driver

Renee McNeil as Board Chairwoman

Suzan Norton as Wall Street Lawyer

Vince Pasani as Wall Street Lawyer

Robert Kim as Elvis Impersonator

Laura Hawkins as Sunny Puppet Dancer

Henry Louis Adams Jr. as Townhouse Guard

Paul Pudney as Dance Instructor

Vanessa Nichole as Vesta Lookalike

Nikki Rush as Vesta Lookalike

Tammy Hurtado as Vesta Lookalike

Emma Anne Wedemeyer as Fake Vesta in Bed

Ivy Lightsey as Lady Justice Statue

Art Newkirk as Saw Law Statue

Savannah Powers as Mournful Lady Statue

Emily Berry as Jane Doe

Adolf Hitler as Self (archive footage) (uncredited)

Benito Mussolini as Self (archive footage) (uncredited)

Matt Gulbranson as New Rome Citizen (uncredited)