Andy Samberg as Jose Canseco

Akiva Schaffer as Mark McGwire

Jorma Taccone as Joe Montana / Walt Weiss / Reporter

Hannah Simone as Amber

Jenny Slate as Stacy

Sterling K. Brown as Sia

Jim O'Heir as Puka Shell Bob

Maya Rudolph as Val Gal #5

Stephanie Beatriz as Val Gal #1

Este Haim as Val Gal #3

Alana Haim as Val Gal #2

Danielle Haim as Val Gal #4

Whitney Moore as Snow Bunny

Dave Faulkner as Mark's Dad

Ben Perez as Jose's Dad

Dan Wicksman as Maitre D'

Denise Weintraub as Mark's Mom

Trinity Chanel as Madonna

Sis Gold as Mrs. MicGillicutty

Kyla Billings as Bikini Babe

Britta Grant as Bikini Babe

Jonetta Kaiser as Bikini Babe

Julia Nolan as Bikini Babe

Jeff Torres as Lenny the Torso

Ryan Nemeth as Hunky Reporter

Tory Taranova as Reporter