Jean Dujardin as Hubert Bonisseur de la Bath / OSS 117

Pierre Niney as Serge / OSS 1001

Wladimir Yordanoff as Armand Lesignac

Fatou N'Diaye as Zéphyrine Bamba

Natacha Lindinger as Micheline Pierson

Gilles Cohen as Roland Lépervier

Pol White as Léon Nkomo

Brice Fournier as Le broussard

Bruno Paviot as Moulinier

Karim Barras as Jacquard

Jean-Édouard Bodziak as Calot

Benoît Joubert as Martichou

Nicolas Bedos as Un homme à l’Hôtel Moderne

Frédéric Vallet as Un membre du gang de Lépervier

Martial Courcier as Jean-Loup

Marie-Gaëlle Cals as Chantal

Emile Abossolo M'bo as Pamplemousse

Ted Etienne as

Balla Habib Dembélé as Koudjo Sangawe Bamba

Christelle Cornil as Josy Le Dentu

Melodie Casta as Jessica pilote russe

Ibrahim Koma as Promedi

Ivan Franěk as Kazimir