Jeff Goldblum as Jamie

Michelle Williams as Halley

Mariel Hemingway as Lesse Hotton

Estella Warren as Arrianne

Omar Epps as J.B.

Peter Gallagher as Guido

Carmen Electra as Simone

Mariska Hargitay as Darcy

Morena Baccarin as Monica

Sônia Braga as Irene Mancini

Angela Bettis as Wilemina

Joanne Baron as Janice Crawford

Michelle Monaghan as Henrietta

Amber Valletta as Blair

Michelle Forbes as Francene

Gaby Hoffmann as Gabrielle Mancini

Carmen Ejogo as Chloe

Leslie Mann as Camille

Kyle MacLachlan as Business Manager

Lucy Gordon as Sarah

Rita Wilson as Roberta

Paul Sorvino as Lorenzo Mancini

Coolio as T

Jared Harris as Anthony

Robert Joy as Andrew

Austin Lysy as Oliver

Harry Hamlin as Hancock

Chris Sarandon as Gary Packer

Troy Garity as Simon

D.W. Brown as Morton

Steven Chester Prince as Denis

Harris Yulin as Phillip

James Wilder as Billy

Michael Sorvino as Mario Mancini

Sloane Shelton as Denise

Pamela Shaw as Rowena

Hunter Carson as Peter McMichaels

Kylie Bax as Maitre D'

Lysa Apostle as Melissa

Frederic Fekkai as Self

GQ as Charlie