Meryl Streep as Alice Hughes

Lucas Hedges as Tyler Hughes

Gemma Chan as Karen

Dianne Wiest as Susan

Candice Bergen as Roberta

Daniel Algrant as Kelvin Krantz

John Douglas Thompson as Dr. Mitchell

Christopher Fitzgerald as Eddie

Mary Catherine Garrison as Customer

Elna Baker as Clovis

Samia Finnerty as Samia

Fred Hechinger as Fred

David Siegel as Karen's Boss

Mike Doyle as Murray Dix

David Shepherd as QM2 Hotel Manager

Stephanie Phippen as Check-in Agent

Dominic Crisonino as Terminal Guide

Barbara Rickard as Autograph Seeker

Haydn Rickard as Autograph Seeker

Hannah James as Salon Receptionist

Andrea Kaiser as QM2 Officer

Al Gwilt as Vernon

Saskia Larsen as Mika (uncredited)

Pete Meads as Hotel Guest (uncredited)