Seth Rogen as Herschel Greenbaum / Ben Greenbaum

Sarah Snook as Sarah Greenbaum

Molly Evensen as Clara

Eliot Glazer as Christian

Kalen Allen as Kevin

Kevin O'Rourke as Dane Brunt

Sean Whalen as Scientist

Geoffrey Cantor as David Greenbaum

Carol Leifer as Susan Greenbaum

Jorma Taccone as Liam

Marsha Stephanie Blake as Inspector Sanders

Alyse Zwick as News Anchor

Dalon Huntington as Border Patrol Agent

Jeremy Michael Grey as Border Patrol Agent

Efka Kvaraciejus as Fish Monger

Darryl Bailey Smith II as Teenage Drone Operator

Dino Rende as Teenage Kid

Peter Kybart as Old Man

Joanna Adler as Professor Kim Ecklund

Herb Mendelsohn as Rabbi

Norm Golden as Wedding Rabbi

Al Nazemian as Cab Driver

Adam Dunhoff as Congregant

Mark Diamond as Congregant

Leib Cohen as Congregant

Liz Cackowski as Susan O'Malley

Tim Robinson as Prosecuting Attorney

Betsy Sodaro as Defense Attorney

Quinta Brunson as Female Interviewee

Kurt Braunohler as Male Interviewee

Michael Weaver as Judge

David Flick as Construction Worker

Raymond Neil Hernandez as Officer Kadushin

John Walpole as Seltzer Man

Ian Poake as Devon

Charles Rogers as Ellis Island Officer

Jess Stark as Female Cashier

Jon Donahue as Local Reporter

Amy Marsalis as Reporter

Paul Monte Jr. as Second Reporter

Julie Mun as Third Reporter

Allan Snyder as Moderator

Fabio Polanco as Audience Member

Havilah Brewster as Second Audience Member

Francis Capone as Manager

Alex McAtee as Bartender

Dionysius Akeem as Cliff

Nick Arapoglou as Todd (uncredited)

Paul Castro Jr. as Freegan (uncredited)

Alexandre Chen as Chinese Worker (uncredited)

Kristin Cochell as Nika (uncredited)

Chuck Filipov as Schlupsk Man (uncredited)

David Mattey as Ivan (uncredited)

Jeff Daniel Phillips as Actor (uncredited)

Adam Ratcliffe as ICE Agent (uncredited)

Estes Tarver as ICE Agent (uncredited)