Bruce Willis as James Cole

Madeleine Stowe as Dr. Kathryn Railly

Brad Pitt as Jeffrey Goines

Christopher Plummer as Dr. Goines

David Morse as Dr. Peters

Jon Seda as Jose

Christopher Meloni as Lt. Halperin

Joey Perillo as Detective Franki

LisaGay Hamilton as Teddy

Matt Ross as Bee

Annie Golden as Woman Cabbie

Michael Chance as Scarface

H. Michael Walls as Botanist

Bob Adrian as Geologist

Bill Raymond as Microbiologist

Ernest Abuba as Engineer

Nell Johnson as Ward Nurse

Rozwill Young as Billings

Joseph Melito as Young Cole

Frank Gorshin as Dr. Fletcher

Aaron Michael Lacey as WWI Sergeant

Vernon Campbell as Tiny

Simon Jones as Zoologist

Carol Florence as Astrophysicist / Jones

Irma St. Paule as Poet

Frederick Strother as L.J. Washington

Charles Techman as Professor

Rick Warner as Dr. Casey

Anthony 'Chip' Brienza as Dr. Goodin

Bruce Kirkpatrick as Policeman No. 1

Wilfred Williams as Policeman No. 2

Joilet Harris as Harassed Mother

Drucie McDaniel as Waltzing Woman Patient

John Blaisse as Old Man Patient

Louis Lippa as Patient at Gate

Stan Kang as X-Ray Doctor

Pat Dias as WWI Captain

Felix Pire as Fale

Karl Warren as Pompous Man

Joseph McKenna as Wallace

Stephen Bridgewater as Airport Detective

Ray Huffman as Plump Businessman

Charley Scalies as Impatient Traveler

Paul Meshejian as Detective Dalva

Kevin Thigpen as Kweskin

Jann Ellis as Marilou

Michael Ryan Segal as Weller

Korchenko as Thug No. 1

Robert O'Neill as Wayne

Harry O'Toole as Louie / Raspy Voice

Chuck Jeffreys as Thug No. 2

Barry Price as Agent No. 1

John Panzarella as Agent No. 2

Janet Zappala as Anchorwoman

Lisa Talerico as Ticket Agent

Tiffany Baldwin as Student in Airport (uncredited)

C.J. Byrnes as Psychiatric Patient (uncredited)

Tom Detrik as FBI Agent (uncredited)

Joe Gerety as Sprayer (uncredited)

Bonnie Loev as Time Portal Nurse (uncredited)

Raymond Mamrak as Travler (uncredited)

Allelon Ruggiero as Inpatient (uncredited)

Thang as Monkey Member (uncredited)

Sal Mazzotta as Prisoner Joey (uncredited)

Bart the Bear as Bear

Donald Faison as Psychiatric Prisoner (uncredited)

Richard Stanley as Man in Transit Lounge (uncredited)

Crispian Sallis as Man (Uncredited)