Jerry O'Connell as Clark Kent / Superman (voice)

Rebecca Romijn as Lois Lane (voice)

Rainn Wilson as Lex Luthor (voice)

Rosario Dawson as Diana Prince / Wonder Woman (voice)

Jason O'Mara as Bruce Wayne / Batman (voice)

Nathan Fillion as Hal Jordan / Green Lantern (voice)

Christopher Gorham as Barry Allen / The Flash (voice)

Matt Lanter as Arthur Curry / Aquaman (voice)

Shemar Moore as Victor Stone / Cyborg (voice)

Nyambi Nyambi as Martian Manhunter (voice)

Rocky Carroll as Silas Stone / Perry White (voice)

Cameron Monaghan as Connor Kent / Superboy (voice)

Charles Halford as Eradicator / Bibbo Bibbowski (voice)

Patrick Fabian as Hank Henshaw (voice)

Erica Luttrell as Mercy Graves (voice)

Max Mittelman as Jimmy Olsen (voice)

Toks Olagundoye as Cat Grant (voice)

Trevor Devall as Dabney Donovan / Bruno Mannheim (voice)

Jonathan Adams as Mayor (voice)

Paul Eiding as Jonathan Kent (voice)

Rick Pasqualone as Turpin (voice)

Jennifer Hale as Martha Kent (voice)

Tony Todd as Darkseid (voice)

Amanda Troop as Sawyer (voice)

Cress Williams as John Henry Irons / Steel (voice)