Bette Midler as Winifred Sanderson

Sarah Jessica Parker as Sarah Sanderson

Kathy Najimy as Mary Sanderson

Whitney Peak as Becca

Belissa Escobedo as Izzy

Lilia Buckingham as Cassie

Froy Gutierrez as Mike

Sam Richardson as Gilbert

Doug Jones as Billy Butcherson

Tony Hale as Mayor / Reverend Traske

Hannah Waddingham as The Witch Mother

Taylor Henderson as Young Winifred

Nina Kitchen as Young Mary

Juju Journey Brener as Young Sarah

Thomas Fitzgerald as John Pritchett

Brett Cramp as Mr. Pritchett

Kim Niemi as Townsperson

Alison Weller as Townsperson

Holly Cinnamon as Townsperson

Patrick French as Townsperson

Charlotte Peed as Mrs. Smith

Ed Peed as Mr. Smith

Austin J. Ryan as Young Billy Butcherson

Michael Tow as Mr. Wilke

Brina as School Secretary

Brian Wiles as Rob

Owen Earls as Liam

Skyla Sousa as Teen Winifred

Aiden Torres as Teen Mary

Emma Kaufman as Teen Sarah

Chhoyang Cheshatsang as Thom

Jaylin Pryor as Teen Gilbert

Marissa Carpio as Food Stall Woman

Naheem Garcia as Fred

Dan Finnerty as Lucas

Joshua Allan Eads as Drag Queen Winifred

Kornbread Jeté as Drag Queen Mary

Kahmora Hall as Drag Queen Sarah

Ryan Rosenthal as Glenn

Juvan Elisma as Alex

Jen D'Angelo as Liam's Mom

Mark Fichera as Scary Scarecrow

Jordan von Netzer as Roman Soldier

Mark Hawker as Puppeteer

Shane Dzicek as Puppeteer

CJ Walsh as Puppeteer

David Torres Jr. as Teacher (uncredited)