John Mulaney as John Mulaney

Jake Gyllenhaal as Mr. Music

Annaleigh Ashford as Crying Lady

Natasha Lyonne as Natasha Lyonne

David Byrne as David Byrne

Richard Kind as Richard Kind

André De Shields as The Tutor

Alexander Bello as Alex

Tyler Bourke as Tyler

Ava Briglia as Ava

Cordelia Comando as Cordelia

Camille De La Cruz as Camille

Oriah Elgrabli as Oriah

Jake Ryan Flynn as Jake

Orson Hong as Orson

Isabella Iannelli as Isabella

Jacob Laval as Jacob

Suri Marrero as Suri

Zell Steele Morrow as Zell

Jonah Mussolino as Jonah

Lexi Perkel as Lexi

Linder Sutton as Linder

Shereen Pimentel as Shereen Pimentel

Phyllis Bash as Phyllis

Erin Quill as Lexi's Mom

Dorothy Stanley as Dorothy

Mary Stout as Mary