Jeff Bridges as Wild Bill Hickok

Ellen Barkin as Calamity Jane

John Hurt as Charley Prince

Diane Lane as Susannah Moore

Keith Carradine as Buffalo Bill Cody

David Arquette as Jack McCall

Christina Applegate as Lurline Newcomb

Bruce Dern as Will Plummer

James Gammon as California Joe

Marjoe Gortner as Preacher

James Remar as Donnie Lonigan

Karen Huie as Song Lew

Peter Jason as Dave McCandless

Steve Reevis as Sioux Chief

Robert Knott as Dave Tutt

Pato Hoffmann as Cheyenne Leader

Patrick Gorman as Doctor

Lee de Broux as Carl Mann

Stoney Jackson as Jubal Pickett

Robert Peters as Mike Williams

Steve Chambers as Curly

Jimmy Medearis as Coke

Jason Ronard as Pink Buford

Dennis Hayden as Phil Coe

Teresa Gilmore as Jessie Hazlitt

Janel Moloney as Earlene

Linda Harrison as Madam

Tricia Munford as Woman in Church

Patricia M. Peters as Dancer