Angourie Rice as Cady Heron

Reneé Rapp as Regina George

Auliʻi Cravalho as Janis ʻImiʻike

Jaquel Spivey as Damian Hubbard

Avantika as Karen Shetty

Bebe Wood as Gretchen Wieners

Christopher Briney as Aaron Samuels

Jenna Fischer as Mrs. Heron

Busy Philipps as Mrs. George

Tina Fey as Ms. Norbury

Tim Meadows as Mr. Duvall

Lindsay Lohan as Mathletes Quizmaster

Jon Hamm as Coach Carr

Ashley Park as Madame Park

Connor Ratliff as Mr. Rapp

Mahi Alam as Kevin Ganatra

John El-Jor as Jason Weems

Brian Altemus as Shane Oman

Megan Thee Stallion as Megan Thee Stallion

Ben Wang as Jacob Zheng

Alexis Frias as Matthew Richmond

Isabella Bria Lopez as Sonja Aquino

Morgen McKynzie as Grace Porter

Veronica S. Taylor as Rachel Hamilton

Stephanie Mincone as Taylor Wedell / Core Dancer

Gabriella Cila as Caitlyn Caussin

Jordan Gallimore as Christian Wiggins

Ari Notartomaso as Lizzie Thurman

Camille Umoff as Dawn Schweitzer

Kaylee Kaleinani as Sophie Kawachi

Allison Winn as Caroline Krafft

Ben Heineman as M. Obo

Fernell Hogan as V. Bowling

Calidore Robinson as S. Martin

Sofia Dobrushin as Teary Girl

Grant Harrison Mateo as Tiny Boy

Amann Iqbal as Rude Girl

Nahscha as Burnout Friend

Gage Roark as Theater Boy

Soona Lee-Tolley as Band Freak

Janna Graham as Band Freak

Matilde Heckler as Band Freak

Francesca Castro as Band Freak

Nuri Park as Choir Girl

Grace Slear as Choir Girl

Izzy Bank as Choir Girl

Kayla LaVine as Choir Girl

James Jones as North Shore Student

Garid Garcia as North Shore Student

Jake Schwencke as North Shore Student

Ellena Eshraghi as North Shore Student

Kelsie Daniels as North Shore Student

Elizabeth Witek as North Shore Student

Alexandra Witek as North Shore Student

Brooke Johnson as Longboarder

Meredith Dunbar as Longboarder

Hank Pekarsky as Teacher

Sri as Social Media Friend

Veronica Merrell-Burriss as Social Media Friend

Vanessa Merrell as Social Media Friend

Jordi as Social Media Friend

Énola Bédard as Social Media Friend

Nia Sioux as Social Media Friend

Emely Moreno as Social Media Friend

Jazz Jennings as Social Media Friend

Pierson Wodzynski as Social Media Friend

Mars Avila as Social Media Friend

Alan Chow as Social Media Friend

Chris Olsen as Social Media Friend

Bailey B. Angelski as Marching Band

Joshua M. Baer as Marching Band

Caitlin M. Beecham as Marching Band

Samantha R. Borsari as Marching Band

Briannon E. Bowman as Marching Band

Ian A. Boyce as Marching Band

Daniela Cassano as Marching Band

Danielle K. Catalano as Marching Band

Ismael Chino as Marching Band

Gianna M. Cologna as Marching Band

Jason L. DeGroff as Marching Band

Kaylin E. DeGroff as Marching Band

Joshua P. Doody as Marching Band

Christiana J. Doyle as Marching Band

Calysta R. Eachus as Marching Band

Kasey L. Ericson as Marching Band

Timothy S. Fletcher as Marching Band

Orlando A. Galazara as Marching Band

Cameron T. Garde as Marching Band

Sean G. Haight as Marching Band

Ryan J. Horgan as Marching Band

Teresa Kissel as Marching Band

Christopher J. Lucey as Marching Band

Megan A. Macneil as Marching Band

Malachi I. McLean as Marching Band

Colin J. McTernan as Marching Band

Julien F. Miller as Marching Band

Lauren M. Molfetta as Marching Band

Meryem G. Oldro as Marching Band

Connor D. Paul as Marching Band

Victoria G. Russo as Marching Band

Olivia C. Tona as Marching Band

Anthony M. Varbaro as Marching Band

Nico A. Varone as Marching Band

Thomas R. Wilson as Marching Band

Haley Fitzgerald as Core Dancer

Jordan Berkman as Core Dancer

Jalen Forward as Core Dancer

Charlize Glass as Core Dancer

Adam Vesperman as Core Dancer

Angelina Barbosa as Dancer

Allison Bedell as Dancer

Elyssa Cueto as Dancer

Joanne Daquigan as Dancer

Keilany Espinal as Dancer

Kyle Hanagami as Dancer

Dougal Herr as Dancer

Megumi Iwama as Dancer

Will Jewett as Dancer

Darriel Johnakin as Dancer

Emily Jo Jordan as Dancer

Shannon Kelly as Dancer

Matthew Kubitz as Dancer

Yashira Maysonet as Dancer

Andrew Mulet as Dancer

Francis Bailey Munoz as Dancer

Malia Murray as Dancer

Diego Pasillas as Dancer

Imani Peterson as Dancer

Annelise Ritacca as Dancer

Kai Rivera as Dancer

Daniel Santiago as Dancer

Hannah Seiden as Dancer

Oriana Siphanoum as Dancer

Effie Tutko as Dancer

Keenan Cooks as Dancer

Jonathan Zeizel as Dancer