Daniel Craig as Will Atenton

Naomi Watts as Ann Patterson

Rachel Weisz as Libby Atenton

Marton Csokas as Jack Patterson

Elias Koteas as Boyce

Taylor Geare as Trish

Claire Geare as Dee Dee

Rachel G. Fox as Chloe Patterson

Jane Alexander as Dr. Greeley

Brian Murray as Dr. Medlin

Bernadette Quigley as Heather Keeler

Sarah Gadon as Cindi

Gregory Smith as Artie

David Huband as Officer Nelson

Martin Roach as Tommy

Lynne Griffin as Sadie

Jonathan Potts as Tony Ferguson

Joe Pingue as Martin

Jean Yoon as New Editor

Marley Otto as Young Author

Nigel Henry as Author's Assistant / Guard 1

Bryon Mumford as Author's Assistant / Guard 2

Ryan Blakely as Harkness Client

Karen Glave as Harkness Receptionist

David Fox as Building Inspector

Adam Chuckryk as Officer Knight (uncredited)

James Collins as Police Officer (uncredited)

Kevin Hanchard as Sgt. Johnson (uncredited)

Kevin B Hartley as Publishing Office Worker

Yulia Lukin as Waitress (uncredited)

Douglas Nyback as Angry Motorist (uncredited)

Chris Owens as Tom Barrion (uncredited)

Robert J. Tavenor as Angrier Motorist (uncredited)

Mark Wilson as Capt. Conklin