Helen Gardner as Cleopatra, Queen of Egypt

Charles Sindelar as Marc Antony, a Triumvir and General

Pearl Sindelar as Iras, Attendant to the Queen

Miss Fielding as Charmian, Attendant to the Queen

Harry Knowles as Kephren, Captain of the Guards to the Queen

Miss Robson as Octavia - Wife of Antony

Helene Costello as Nicola - a Child