Channing Tatum as George Washington (voice)

Jason Mantzoukas as Samuel Adams (voice)

Olivia Munn as Thomas Edison (voice)

Bobby Moynihan as Paul Revere (voice)

Judy Greer as Martha Washington (voice)

Will Forte as Abraham Lincoln (voice)

Raoul Max Trujillo as Geronimo (voice)

Killer Mike as Blacksmith (voice)

Simon Pegg as King James (voice)

Andy Samberg as Benedict Arnold (voice)

Carlos Alazraqui as Clyde (voice)

Jason Barnes as Redcoat Soldier (voice)

David Callaham as Rights Man In Crowd / I.M. Pei (voice)

Christian Danley as A Reasonable Man / Bros / Redcoat Soldier (voice)

Kevin Gillese as John Wilkes Booths / Titanic Guard (voice)

Iyad Hajjaj as Civil Rights Man In Crowd (voice)

Neal Holman as Colonist / Continental Congressman / Field Marshall (voice)

J. LaRose as Native American Rights Man In Crowd (voice)

Megan Leahy as Clara Barton (voice)

Amber Nash as Street Race Girl / Women's Rights Lady In Crowd (voice)

Eric Sims as Thomas Jefferson (voice)

Mike Schatz as Frederick X Kinko / Hancock Supporter (voice)

Lucky Yates as Baseball Announcer / 2nd Amendment Rights Man In Crowd (voice)